CROWN BIOSCIENCE|Biospecimen Services

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Translational Biology · Biospecimens · Multi-omics Services

From Specimen to Insight. Your Translational Biology Partner for Precision Oncology.
From Discovery to Clinic.

Accelerate your drug discovery with high quality biospecimens
optimized for multi-omics and precision oncology. We partner with
pharma, biotech, and diagnostics teams to deliver the ethically
sourced samples and science that move programs forward.

Discuss Your Program
Our Capabilities
20+

Years of biobank science since founding in 2002

GCP

Clinical-grade laboratory operations & CAP proficiency

100+

Validated multi-omics assays with 8 annual CAP proficiency test programs

25+

Tumor types with matched tissue and biofluid pairs

Our Approach

What Makes Our Science Different

Every step in our workflow – from the operating room to the biobank storage to the assay bench – is designed to preserve the molecular integrity your discovery, translational, and clinical applications depend on.

The primary challenge in modern drug discovery is the scarcity of ethically sourced human biospecimens that maintain molecular integrity while providing deep clinical context. Traditional biobanking often suffers from fragmented data and inconsistent collection protocols, leading to “noisy” experimental results and failed biomarker validation.

IRB-Approved Collections

All specimens collected under IRB-approved protocols with documented informed consent and full traceability

Global Clinical Network

Partnerships across oncology practices in Germany and internationally, enabling prospective and custom collections

In-House Pathology

Board-certified pathologists review all tissue specimens and IHC results on site

Regulated environement

ISO, CAP and GCP operations

HIPAA & GDPR

Full compliance with US and EU data privacy regulations

CAP proficiency

8 annual proficency test programs, maintaining accreditation standards

Ultra-Short Ischemic Time

Standardized protocols minimize the time in the surgical suite between excision and preservation, protecting the integrity of RNA, DNA, and protein signatures within the tissue. This ensures that downstream analyses – whether NGS, spatial transcriptomics, or proteomic profiling- reflect true tumor biology rather than collection artifact.

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Deep Clinical Annotation

Every specimen includes treatment history, demographics, pathological confirmation, and therapy response data – over 300 data points are collected via our partner clinics. Build patient cohorts with the specificity your study design requires.

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Biobanking Standards

State-of-the-art biobanking facilities designed for optimal collection, processing, and storage of biological samples and clinical data.

Surgical Human Biobank

Curated for Oncology. Characterized for Translation.

FFPE, fresh-frozen, mutation-characterized, and viable fresh tissue across 25+ tumor
types, with matched biofluids available for integrated analyses.

Tumor, Metastasis & Adjacent Normal

Prospective and banked collections

Tissue Formats

Available for immediate or prospective collection

Matched Biofluids

Available paired with tissue specimens

Find the Right Samples for Your Study

Search our inventory or request a custom collection tailored to your specific inclusion/exclusion criteria. Our team of scientists is ready to help you select the ideal cohorts for your next project.

Biospecimen Request

Longitudinal Plasma Collections

Monitor Disease Evolution Across the Treatment Journey

Tracking disease progression requires more than a snapshot. Our longitudinal plasma collections offer a window into the evolution of cancer, providing serial samples from the same patient across various treatment milestones. This is an essential resource for researchers developing non-invasive diagnostics or monitoring drug resistance mechanisms – across 20+ cancer indications and 9+ therapy classes including checkpoint inhibitors, chemotherapy, and targeted therapies.

  • Baseline / Pre-Treatment Plasma collected at diagnosis before therapy initiation
  • On-Treatment Monitoring Serial draws at defined intervals during active therapy
  • Response Assessment Samples correlated with imaging and clinical response data
  • Progression / Resistance Capture molecular changes at disease progression

Capabilities

Multi-Omics Laboratory Services across all therapeutic areas

Pre-clinical and clinical workflows operated under GCP or non-GCP, depending on your
study requirements. Available as standalone services or integrated with our
biospecimens. All pathology reviewed by in-house board-certified pathologists.

IHC & Spatial Biology

Chromogenic and multiplex fluorescent immunohistochemistry with integrated digital pathology and image analysis for spatial protein expression characterization.

Histopathology

Full-service tissue processing, staining, and expert pathological evaluation — from routine H&E to specialized stains and tissue microarray (TMA) preparation.

Genomics & Transcriptomics

From nucleic acid isolation through single-cell resolution and spatial context — the full spectrum of genomic analysis for translational research.

Proteomics & Cell Biology

Protein-level analysis and functional cell-based assays — from immunoassays to ex vivo drug profiling on patient-derived material.

Quality & Compliance

Built for Regulated Research

IRB-Approved

Documented informed consent protocols

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HIPAA & GDPR

US and EU data privacy compliance

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GCP Operations

Clinical-grade laboratory workflows

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CAP Proficiency

8 annual proficency test programs

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In-House Pathology

Board-certified pathologist review

Let’s Build Your Translational Program

Whether you need biospecimens for a research study, standalone laboratory
services, or a fully integrated translational biology program — our scientific
team is ready to partner with you.

Contact Our Team

US: +1 (301) 228 9739

Germany: +49 40 69 63 572 0

busdev@biospecimenservices.com

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CROWN BIOSCIENCE|Global Biospecimen & Scientific Services

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